KLHL13 (8D1) Antibody

Cat no: 253027

Supplier: ABBIOTEC

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Description
Additional Information

KLHL13 (Kelch-like protein 13) is a 604 amino acid long protein that contains si, Xenopus/Amphibian, Kelch repeats and one BTB/POZ domain. E, Xenopus/Amphibian,pressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase comple, Xenopus/Amphibian,. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase.

Catalogue number:	253027
Reactivities:	Human
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	Q9P2N7
Antigen:	Purified recombinant fragment of human KLHL13 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	8D1
Additional info:	Kelch-like protein 13; BTB and kelch domain-containing protein 2; BKLHD2; KIAA1309; KLHL13