KLHL21 (2H4) Antibody

Cat no: 253023

Supplier: ABBIOTEC

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Description
Additional Information

KLHL21 (Kelch-like protein 21) protein is part of the ubiquitin-proteasome pathway. It is a substrate-specific adapter of a BCR (BTB-CUL3-RB, Xenopus/Amphibian,1) E3 ubiquitin-protein ligase comple, Xenopus/Amphibian, required for efficient chromosome alignment and cytokinesis. The BCR (KLHL21) E3 ubiquitin ligase comple, Xenopus/Amphibian, regulates localization of the chromosomal passenger comple, Xenopus/Amphibian, (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase comple, Xenopus/Amphibian, may not lead to its degradation by the proteasome.

Catalogue number:	253023
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	Q9UJP4
Antigen:	Purified recombinant fragment of human KLHL21 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	2H4
Additional info:	KIAA0469; MGC99635; KLHL21; Kelch-like protein 21