KLHL22 (7B10) Antibody

Cat no: 253068

Supplier: ABBIOTEC

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Description
Additional Information

KLHL22 (Kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains si, Xenopus/Amphibian, kelch repeats and one BTB (POZ) domain. The BTB (Broad-Comple, Xenopus/Amphibian,, Tramtrack and Bric a brac) domain, also known as the POZ (Po, Xenopus/Amphibian,virus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.

Catalogue number:	253068
Reactivities:	Human
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	Q53GT1
Antigen:	Purified recombinant fragment of human KLHL22 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	7B10
Additional info:	KELCHL; KLHL22; Kelch-like protein 22