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L-Dicentrine

Cat no: 009121


Supplier: United States Biological
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A natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive antagonism and could be a potential muscle relaxant. Studies suggest that it has protective effect of on acute myocardial Iichemia and anoxia lesion.
Catalogue number: 009121
Size: 10mg
Alternative names: (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; 9,10-Dimethoxy-1,2-(methylenedioxy)-6ab-aporphine; (R)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; (-)-Dicentrine; (R)-(-)-Dicentrine; NSC 251699;
References: Li, H. et al.: Zhong. Zhon. Zaz., 25, 426 (2000); Li, M. et al.: Acad. J. Kun. Med. Coll., 1003 (1997); Teng, C.M. et al.: Brit, J. Pharmacol., 104, 651 (1991);

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