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LAGE3, Recombinant, Human, aa1-143, His-Tag (L Antigen Family Member 3, CVG5, DXS9879E, DXS9951E, ESO3, ITBA2)

Cat no: 137104

LAGE3, Recombinant, Human, aa1-143, His-Tag (L Antigen Family Member 3, CVG5, DXS9879E, DXS9951E, ESO3, ITBA2)

L antigen family member 3, also known as LAGE3, belongs to the CTAG family. Members of the LAGE/ESO gene family are clustered together on human chromosome Xq28 and have similar exon-intron structures. Unlike the other family members, which are normally expressed only in testis and activated in a wide range of human tumors, LAGE3 is ubiquitously expressed in somatic tissues. This protein is also highly conserved in mouse and rat, suggesting that the encoded protein is functionally important. \n\nSource: \nRecombinant protein corresponding to human LAGE3, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~17.2kD (166aa) (MALDI-TOF)\n\nAA Sequence:\n MGSSHHHHHH SSGLVPRGSH MGSMRDADAD AGGGADGGDG RGGHSCRGGV DTAAAPAGGA PPAHAPGPGR DAASAARGSR MRPHIFTLSV PFPTPLEAEI AHGSLAPDAE PHQRVVGKDL TVSGRILVVR WKAEDCRLLR ISVINFLDQL SLVVRTMQRF GPPVSR\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137104

Size

20ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.15M NaCl, 50% glycerol, 2mM DTT.

Purity

~85% (SDS-PAGE)

References

1. Alpen B., et al. (2002) Gene. 297:141-149.

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