LAL (9G7F) Antibody

Cat no: 252646

Supplier: ABBIOTEC

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Description
Additional Information

LAL (Lysosomal acid lipase) is a 378-amino acid (~43-54 kDa) protein. It is found in the lysosomes to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. It is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs,Porcinearticularly in liver, spleen, the adrenal and the hemopoietic system, also in the intestine as well as in the lymph nodes, lungs, testes and ovaries.

Catalogue number:	252646
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	P38571
Antigen:	Purified recombinant fragment of LAL e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2a
Clonality:	9G7F12,7G6D7
Additional info:	Lysosomal acid lipase/cholesteryl ester hydrolase; Acid cholesteryl ester hydrolase; LAL; Cholesteryl esterase; Lipase A; Sterol esterase