Lck (8E5F) Antibody

Cat no: 252663

Supplier: ABBIOTEC

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Description
Additional Information

Lck (Lymphocyte-specific protein tyrosine kinase) is a 509-amino acid protein (~56kDa), belongs to the Src non-receptor tyrosine kinases family. The Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is e, Xenopus/Amphibian,pressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant e, Xenopus/Amphibian,pression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. Inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection.

Catalogue number:	252663
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	Q9UQQ2
Antigen:	Purified recombinant fragment of human Lck e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2a
Clonality:	8E5F9, 4B2C7
Additional info:	SH2B adapter protein 3; Lymphocyte adapter protein; Lymphocyte-specific adapter protein Lnk; Signal transduction protein Lnk; LNK; SH2B3