LEAF(TM) anti-mouse CD66a (CEACAM1a)

CD66a, known as CEACAM1a, carcinoembryonic antigen-related cell adhesion molecule 1a, is a glycoprotein of the immunoglobulin superfamily and the carcinoembryonic antigen family. Isoforms expressing either two or four alternatively spliced Ig-like domains in mice have been found in a number of epithelial, endothelial, or hematopoitic tissues. CEACAM1a functions as an intercellular adhesion molecule, an angiogenic factor, and a tumor cell growth inhibitor. It also serves as a signal regulatory protein influencing B cell receptor complex-mediated activation. Moreover, the mouse CEACAM1a protein is targets of viral or bacterial pathogens. It was reported that targeted disruption of the CEACAM1a gene resulting in a partial ablation of the protein in mice led to reduced susceptibility to virus infection. The antibody recognizes the N-terminal domain of murine CEACAM1a, does not recognize murine CEACAM1b, an allele in SJL mice.

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SPECIFICATIONS

Catalog Number

134504

Size

500 microg

Applications

BNI, ELISA, FC, IHC, IP, WB

Hosts

Mouse

Reactivities

Mouse

Clone

MAb-CC1

Antigen

Balb/c mouse purified intestinal brush border membrane

Gene Id

26365

Isotype

Mouse IgG1

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

1 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C. This LEAF(TM) Purified solution contains no preservative; handle under aseptic conditions.

Alternative Names

CEACAM, CEACAM1a, Bgp

Regulatory Status

RUO