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LEAF(TM) anti-mouse CD66a (CEACAM1a)

LEAF(TM) anti-mouse CD66a (CEACAM1a)

Cat no: 134504

Supplier: BioLegend
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CD66a, known as CEACAM1a, carcinoembryonic antigen-related cell adhesion molecule 1a, is a glycoprotein of the immunoglobulin superfamily and the carcinoembryonic antigen family. Isoforms expressing either two or four alternatively spliced Ig-like domains in mice have been found in a number of epithelial, endothelial, or hematopoitic tissues. CEACAM1a functions as an intercellular adhesion molecule, an angiogenic factor, and a tumor cell growth inhibitor. It also serves as a signal regulatory protein influencing B cell receptor complex-mediated activation. Moreover, the mouse CEACAM1a protein is targets of viral or bacterial pathogens. It was reported that targeted disruption of the CEACAM1a gene resulting in a partial ablation of the protein in mice led to reduced susceptibility to virus infection. The antibody recognizes the N-terminal domain of murine CEACAM1a, does not recognize murine CEACAM1b, an allele in SJL mice.
Catalogue number: 134504
Reactivities: Mouse
Hosts: Mouse
Applications: Block/Neutralize/Inhibit, ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 500 microg
Clone: MAb-CC1
Gene: 26365
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) Purified solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: Balb/c mouse purified intestinal brush border membrane
Isotype: Mouse IgG1
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: CEACAM, CEACAM1a, Bgp
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