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LEAF(TM) Purified anti-human CD119 (IFN-gamma R alpha chain)

LEAF(TM) Purified anti-human CD119 (IFN-gamma R alpha chain)

Cat no: 308604

Supplier: BioLegend
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CDw119 is a 90-100 kD type I transmembrane protein, also known as IFN-gamma R alpha chain or IFN-gammaRI. The IFN-gamma receptor is a complex of a high affinity IFN-gamma-binding chain (aka, IFN-gamma R alpha chain) and a second accessory protein required for signal transduction known as IFN-gamma R beta chain. The IFN-gamma R alpha chain is a member of the class II cytokine receptor family. Binding of IFN-gamma induces receptor dimerization and internalization. Signal transduction involves Jak1 and Jak2 protein kinases and involves STAT1 activation. The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Catalogue number: 308604
Reactivities: Human
Hosts: Mouse
Applications: Block/Neutralize/Inhibit, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 500 microg
Clone: GIR-208
Gene: 3459
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: Human IFN-gammaRalpha, Purified from human placenta
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: IFN-gammaR, IFN-gammaRalpha, IFN-alpha R1, CDw119
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