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LEAF(TM) Purified anti-human CD129 (IL-9 R)

LEAF(TM) Purified anti-human CD129 (IL-9 R)

Cat no: 310408

Supplier: BioLegend
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CD129 is known as the 57 kD IL-9 receptor. It is a member of the hematopoietin receptor superfamily. Although the alpha-chain of the receptor binds IL-9 with high affinity, interaction with the gamma-chain (CD132) of the IL-2 receptor is required for signaling. The IL-9 receptor is expressed at low levels on eosinophils, mast cells, macrophages, B lymphocytes, T lymphocytes, and erythroid progenitors. IL-9 receptor binding initiates STAT activation required for the proliferative and anti-apoptotic effects of this cytokine. In humans, signals from the IL-9 receptor appear to be critical for intrathymic T cell development. IL-9 binding has been shown to increase IL-5 receptor expression and promote survival in human eosinophils.
Catalogue number: 310408
Reactivities: Human
Hosts: Mouse
Applications: Block/Neutralize/Inhibit, ELISA, Flow Cytometry
Size: 500 microg
Clone: AH9R7
Gene: 3581
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.5 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Isotype: Mouse IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: IL-9 Receptor, IL-9R
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