LEAF(TM) Purified anti-human IL-12/IL-23 p40

Cat no: 508803

Supplier: BioLegend

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Description
Additional Information

The C8.6 antibody reacts with human IL-12 p40 subunit of the IL-12 p70 heterodimer and IL-23 p40 subunit of the IL-23 p19/p40, as well as p40 monomer and homodimer. The C8.6 antibody has been reported to strongly inhibit different biological activities of IL-12, (e.g., IFN-gamma induction, mitogenic effects on PHA blasts, and enhancement of NK cell-mediated cytotoxicity). The C8.6 antibody can neutralize the bioactivity of natural or recombinant IL-12.

Catalogue number:	508803
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Size:	50 microg
Clone:	C8.6
Gene:	3593
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.125 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Antigen:	COS-expressed p40 subunit of human IL-12
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Interleukin-12 p40, p40 subunit of IL-12 and IL-23, CLMF p40, NKSF p40, TcMF p40, TSF p40