LEAF(TM) Purified anti-human/mouse CXCR7

Cat no: 331110

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and few other cell types.

Catalogue number:	331110
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	500 microg
Clone:	8F11-M16
Gene:	12778,57007
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Antigen:	Human CXCR7 transfectant
Isotype:	Mouse IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	RDC1, G protein-coupled receptor, chemokine (C-X-C motif) receptor 7

See Full Product Listings >

LEAF(TM) Purified anti-human/mouse CXCR7

Cat no: 331110

About Biosave

Product Categories

Information