LEAF(TM) Purified anti-mouse alpha-GalCer:CD1d complex

Cat no: 140504

Supplier: BioLegend

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Description
Additional Information

The L363 antibody reacts with alpha-GalCer:mouse CD1d complex. Glycolipid alpha-galactosylceramide (alpha-GalCer) is a potent activator of human and murine iNKT cells and is widely used as a model antigen for the studies of iNKT-mediated immunity. The glycolipid binds to CD1d and forms a complex which is subsequently recognized by iNKT cells, a subset of T cells expressing invariant TCR alpha chain Valpha14, analogous to the peptide-MHC complex recognition by TCR alpha/ß T cells.

Catalogue number:	140504
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Block/Neutralize/Inhibit, Flow Cytometry, Immunofluorescence
Size:	500 microg
Clone:	L363
Gene:	12479
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Antigen:	alpha-GalCer:mCD1d1 complexes coupled to Mycobacterium tuberculosis PPD
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C