LEAF(TM) Purified anti-mouse CD106

Cat no: 105708

Supplier: BioLegend

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Description
Additional Information

CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (alpha4/beta1 integrin) and LPAM-1 (alpha4/beta7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.

Catalogue number:	105708
Reactivities:	Mouse
Hosts:	Rat
Applications:	Block/Neutralize/Inhibit, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size:	500 microg
Clone:	429 (MVCAM.A)
Gene:	22329
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Antigen:	Mouse preadipose cell line PA6
Isotype:	Rat IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	VCAM-1, INCAM-110