LEAF(TM) Purified anti-mouse CD132 (common gamma chain)

Cat no: 132304

Supplier: BioLegend

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Description
Additional Information

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common gamma chain (gammac) or IL-2 receptor gamma subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Catalogue number:	132304
Reactivities:	Mouse
Hosts:	Rat
Applications:	Block/Neutralize/Inhibit, Flow Cytometry
Size:	500 microg
Clone:	TUGm2
Gene:	16186
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Isotype:	Rat IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Leu-20, FceRII, BLAST-2, B6, Low affinity IgE receptor