LEAF(TM) Purified anti-mouse CD18

Cat no: 101410

Supplier: BioLegend

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Description
Additional Information

CD18 is a 95 kD protein, also known as integrin beta2 subunit. It is expressed on all leukocytes. CD18, in association with integrin alpha chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and alphaXbeta2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.

Catalogue number:	101410
Reactivities:	Mouse
Hosts:	Rat
Applications:	Block/Neutralize/Inhibit, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size:	500 microg
Clone:	M18/2
Gene:	16414
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Antigen:	Mouse CTL glycoprotein
Isotype:	Rat IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Integrin beta2 subunit, b2 integrin