LEAF(TM) Purified anti-mouse CD255 (TWEAK)

Cat no: 120008

Supplier: BioLegend

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Description
Additional Information

TWEAK is a 27 kD protein also known as tumor necrosis factor superfamily member 12 (TNFSF12), TNF-related weak inducer of apoptosis, and CD255. TWEAK is a type II transmembrane protein expressed on a variety of cell types. A soluble form of TWEAK is produced by proteolytic processing. TWEAK binds to the TWEAK receptor, FN14, to induce apoptosis, NF-kappaB translocation, and promote angiogenesis and endothelial cell proliferation. It has also been implicated in the induction of inflammatory cytokines.

Catalogue number:	120008
Reactivities:	Mouse
Hosts:	Rat
Applications:	Block/Neutralize/Inhibit, Flow Cytometry
Size:	500 microg
Clone:	MTW-1
Gene:	21944
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance in each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Isotype:	Rat IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	TNF-related weak inducer of apoptosis, CD255, TNFSF12,