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LEAF(TM) Purified anti-mouse CD31

LEAF(TM) Purified anti-mouse CD31

Cat no: 102512

Supplier: BioLegend
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CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (alphav beta3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis. The MEC13.3 antibody has been shown to inhibit in vitro and in vivo functions of CD31.
Catalogue number: 102512
Reactivities: Mouse
Hosts: Rat
Applications: Block/Neutralize/Inhibit, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 500 microg
Clone: MEC13.3
Gene: 18613
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: Polyoma middle T transformed EC line tEnd.1
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: PECAM-1, EndoCAM, gpIIa
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