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LEAF(TM) Purified anti-mouse CD47

LEAF(TM) Purified anti-mouse CD47

Cat no: 127512

Supplier: BioLegend
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CD47, also known as Integrin-Associated Protein (IAP) ,is a membrane protein of about 50 kd with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region.It is widely expressed on many cell types and often associated with beta 3 integrins.The significance of this molecules is recently drawing increasing attention.It has been reported that CD47 functions as a self marker.Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages.By binding to SIRPalpha,CD47 controls hemostatic innate immune functions,such as phagocytosis and cell trafficking.
Catalogue number: 127512
Reactivities: Mouse
Hosts: Rat
Applications: Block/Neutralize/Inhibit, Flow Cytometry
Size: 500 microg
Clone: miap301
Gene: 16423
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Integrin-associated protein, IAP, neurophilin,gp42, Rh-associated protein
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