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LEAF(TM) Purified anti-mouse DR3 (TNFRSF25)

LEAF(TM) Purified anti-mouse DR3 (TNFRSF25)

Cat no: 144403

Supplier: BioLegend
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DR3, also known as TNFRSF25, lymphocyte-associated receptor of death (LARD), WSL-1, TRAMP, TR3 and APO3, is a 55 kD glycoprotein belonging to the TNF receptor superfamily (TNFRSF). TNFSF25 is expressed at low level on CD4-positive, CD8-positive T cells and NKT cells. It has been shown to stimulate NF-kappaB activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domains containing adaptor proteins. Recently, it has been shown that TNFRSF25 is also expressed on Treg cells and regulates Treg proliferation.
Catalogue number: 144403
Reactivities: Mouse
Applications: Flow Cytometry
Size: 50 microg
Clone: 4C12
Gene: 85030
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis on mouse DR3 transfected cells. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: Mtnfr25-Ig fusion protein
Isotype: Armenian Hamster IgG1, lambda
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Apo-3, LARD, TNFRSF25, TNFR25, TRAMP, WSL-1, DR3, Apo3, TNFRSF 25, WSL1
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