LEAF(TM) Purified anti-mouse/human CD11b

Cat no: 101231

Supplier: BioLegend

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Description
Additional Information

CD11b is a 170 kD glycoprotein also known as alphaM integrin, Mac-1 alpha subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (beta2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Catalogue number:	101231
Reactivities:	Human, Mouse
Hosts:	Rat
Applications:	Block/Neutralize/Inhibit, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Size:	1 mg
Clone:	M1/70
Gene:	16409, 3684
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Antigen:	C57BL/10 splenocytes
Isotype:	Rat IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Integrin aM, alphaM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR