LEAF(TM) Purified anti-mouse/human CD258 (LIGHT)

Cat no: 137104

Supplier: BioLegend

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Description
Additional Information

CD258, also known as LIGHT, belongs to the tumor necrosis factor (TNF) superfamily. CD258 is a homotrimer composed of type II single-pass chains. The cleavage of this molecule from the cell surface results in a soluble form of LIGHT. CD258 stimulates T cell proliferation, CTL activity, Th1 cytokine production and induces apoptosis in some tumor lines. CD258 is expressed by T cells, NK cells, macrophages and platelets. The receptors of LIGHT are HVEM, LTbetaR and DCR3. CD258 has an important role in the cell-mediated immune response and in graft versus host disease.

Catalogue number:	137104
Reactivities:	Human, Mouse
Hosts:	Mouse
Applications:	Block/Neutralize/Inhibit, ELISA, Immunoprecipitation
Size:	500 microg
Clone:	15B2
Gene:	50930, 8740
Dilutions:	Each lot of this antibody is quality control tested by ELISA. For ELISA, the suggested use of this reagent is 10 microg/ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration:	1 mg/ml
Antigen:	Recombinant extracellular domain of murine LIGHT
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	LIGHT, TNFSF14, LTgamma, HVEM-L, Ly113, TR2