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LEAF(TM) Purified anti-mouse/rat IL-1beta

LEAF(TM) Purified anti-mouse/rat IL-1beta

Cat no: 503504

Supplier: BioLegend
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IL-1 refers to two proteins, IL-1alpha and IL-1beta which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1beta is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. The B122 antibody reacts with the precursor and mature secreted forms of mouse IL-1beta. This antibody also recognizes rat IL-1beta. The B122 antibody can neutralize the bioactivity of natural or recombinant IL-1beta.
Catalogue number: 503504
Reactivities: Mouse, Rat
Hosts: Hamster
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 500 microg
Clone: B122
Gene: 16176
Dilutions: Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 2-6 microg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-1beta recombinant protein ranging from 2000 to 30 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: E. coli -expressed, recombinant mouse IL-1beta
Isotype: Armenian Hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Interleukin-1beta, Catabolin, H1, IFNbeta-inducing factor, OAF
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