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LEAF(TM) Purified anti-mouse TCR gamma/delta

LEAF(TM) Purified anti-mouse TCR gamma/delta

Cat no: 118114

Supplier: BioLegend
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T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR alpha/beta) or a gamma and a delta chain (TCR gamma/delta). TCR gamma/delta belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. gamma/delta TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most gamma/delta T cells are CD4-/CD8- although some are CD8+. T cells expressing the gamma/delta TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that gamma/delta T cells also play a principal role in antigen presentation.
Catalogue number: 118114
Reactivities: Mouse
Hosts: Hamster
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 500 microg
Clone: GL3
Gene: 110066,110067
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: C57BL/6J intraepithelial lymphocytes
Isotype: Hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: T cell receptor gamma/delta, g/d TCR, TCR-g/d
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