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LEAF(TM) Purified anti-mouse TLR4 (CD284)/MD2 Complex

LEAF(TM) Purified anti-mouse TLR4 (CD284)/MD2 Complex

Cat no: 117607

Supplier: BioLegend
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Toll-like receptors are highly conserved from Drosophila to humans and share structural and functional similarities. They are type I transmembrane signaling receptors which activate the innate immune system in response to pathogen invasion. So far, at least 13 TLR members have been identified. The secretory protein, MD2, associates with cell-surface bound TLR4 (CD284) on monocytes, B cells and T cells. TLR4 has been recognized as critical for host recognition of bacterial LPS in conjunction with MD2.
Catalogue number: 117607
Reactivities: Mouse
Hosts: Rat
Applications: Block/Neutralize/Inhibit, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Size: 50 microg
Clone: MTS510
Gene: 21898
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: Ba/F3 cell line transfected with mouse TLR4 /MD2 complex
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Toll-like Receptor 4/MD2 Complex, TLR4/MD2 Complex
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