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LEAF(TM) Purified anti-mouse VEGF-A

LEAF(TM) Purified anti-mouse VEGF-A

Cat no: 512808

Supplier: BioLegend
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VEGF-A, also known as VEGF (vascular endothelial growth factor), is the founding member of the family including VEGF (VEGF-A), VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. Vascular endothelial growth factors (VEGFs) are a family of secreted polypeptides with a highly conserved receptor-binding cystine-knot structure similar to that of the platelet-derived growth factors.VEGF-A has important roles in mammalian vascular development and in diseases involving abnormal growth of blood vessels such as tumor-related angiogenesis.VEGF-A is produced by diverse cell types, including aortic vascular smooth muscle cells, keratinocytes, macrophages and many tumor cells. Oxygen tension is a key physiological regulator of VEGF-A gene expression.
Catalogue number: 512808
Reactivities: Mouse
Hosts: Rat
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 500 microg
Clone: 2G11-2A05
Gene: 22339
Dilutions: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 2.5-10 microg antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The VEGF-A antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: N-terminal 24 aa sequence of murine VEGF
Isotype: Rat IgG, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Vascular endothelial growth factor (VEGF), VEGF-A
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