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LEGEND MAX(TM) Human IL-17A/F ELISA Kit with Pre-coated Plates

LEGEND MAX(TM) Human IL-17A/F ELISA Kit with Pre-coated Plates

Cat no: 435807


Supplier: BioLegend
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Human IL-17A/F is a heterodimeric member of the IL-17 family It is a pro-inflammatory cytokine secreted by activated Th17 cells in response to bacteria and fungi. There is great interest in IL-17 family members, not only for their role in adaptive immunity and inflammation, but also in a variety of auto-immune diseases, such as Crohn's disease, ulcerative colitis, psoriasis, multiple sclerosis, rheumatoid arthritis, asthma, and lupus. IL-17A/F consists of the monomeric units of IL-17A and IL-17F, which share 50% amino acid sequence identity. It has been shown to be a naturally expressed and biologically active molecule. While much has been studied about IL-17A and IL-17F, it is still unclear how each distinctively induces the inflammatory response, and what role IL-17A/F also plays in it. It is known that all three cytokines are produced in different amounts, and each has different degrees of pro-inflammatory effects. All seem to interact with the IL-17RA/IL-17RC receptor complex, and signal via the NF-kappaB pathway to induce secretion of inflammatory cytokines and recruit granulocytes. BioLegend's LEGEND MAX(TM) Human IL-17A/F ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA), in which, a specific antibody is pre-coated on a 96-well strip-well plate. BioLegend's LEGEND MAX(TM) Human IL-17A/F ELISA Kit is specifically designed for the accurate quantitation of Human IL-17A/F from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive.
Catalogue number: 435807
Reactivities: Human
Applications: ELISA
Size: 1 Pre-coated Plate
Gene: 3605, 112744
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Interleukin-17A/F, IL-17A/IL-17F (IL17A/IL17F), IL17A/F Precoated ELISA Kit
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