Mouse IL-17A (synonyms include IL-17, IL-17a, Cytotoxic T Lymphocyte-Associated Antigen-8 [CTLA-8]) is a founding member of the IL-17 family of cytokines. IL-17 is mainly produced by Th17 cells, a small subset of T helper cells. IL-17 exhibits multiple biological activities including the induction of various proinflammatory cytokines and chemokines such as IL-6, IL-8, G-CSF, GM-CSF, GRO-alpha, and MCP-1 on a variety of cell types. IL-17 is also involved in the activation of NF-kB and costimulation of T cell proliferation. As a result of these roles, IL-17 has been linked to many immune and autoimmune-related diseases including rheumatoid arthritis, asthma, lupus and multiple sclerosis.BioLegend’s LEGEND MAX(TM) Mouse IL-17A ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA), in which, a Mouse IL-17A specific monoclonal antibody is pre-coated on a 96-well strip-well plate.BioLegend’s LEGEND MAX(TM) Mouse IL-17A ELISA Kit is specifically designed for the accurate quantitation of Mouse IL-17A from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive.
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