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Leptin, Recombinant, Human (Biotin) (Ob, Obese Protein, Obesity Factor)

Cat no: L1670-15B

Leptin, Recombinant, Human (Biotin) (Ob, Obese Protein, Obesity Factor)

Leptin, the product of the ob (obese) gene, is a 16kDa protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function. \n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nStorage and Stability:\nFor long-term storage and to avoid repeated freezing and thawing, aliquot and freeze at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

L1670-15B

Size

100ug

Applications

ELISA, WB

Conjugates

Biotin

Form

Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin. No preservative and no stabilizing protein added.

Purity

(same/more than)95% (SDS-PAGE and HPLC analyzed).

References

Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.: Positional Cloning of the Mouse Obese Gene and its Human Homologue. Nature 372, 425

Additional Info

Recombinant human leptin is 100% homologous with the human serum leptin.

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