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Leptin, Recombinant, Human (Ob, Obese Protein, Obesity Factor)

Cat no: L1670-15

Leptin, Recombinant, Human (Ob, Obese Protein, Obesity Factor)

Human leptin (Anti-Obesity Protein) is the human homologue of murine leptin, the protein product of the ob (obese) gene in mice which seems to be involved in appetite control. The murine ob gene is expressed in adipose tissue and is thought to regulate the body's fat stores. It targets the central nervous system, particularly hypothalamus, affecting food intake. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Human leptin is a 16.0kD protein containing 147 amino acid residues.\n\nSource: E. coli\n\nSpecificity: Recombinant human leptin is 100% homologous with the human serum leptin. \n\nForm: Sterile filtered and lyophilized from 0.5mg/ml in 10mM sodium citrate, pH 4.0\n\nPurity: (same/more than) 95% by SDS-PAGE\n\nProtein Content: 0.1mg (determined by BCA method)\n\nConcentration: ~0.5mg/ml Protein\n\nEndotoxin: 0.1ng/ug (1EU/ug)\n\nQuality Control: BCA

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SPECIFICATIONS

Catalog Number

L1670-15

Size

200ug

Applications

ELISA, WB

References

US Biological application reference: Wilson, M.E. et al., (2005) Physiol Behav. 84:449-458. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.:

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