Quick Search
Products Leptomycin B, Free Acid (Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin)
| Catalogue number: | L1671-38B |
| Size: | 100ug |
| Form: | Supplied as a clear, colorless solution in absolute ethanol. |
| Purity: | ~99% |
| References: | 1. Fukuda. M., et al. "CRM1 is responsible for intracellular transport mediated by the nuclear export signal." Nature 390:308-311 (1997). 2. Kudo, N., et al. "Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region." Proc. Natl. Acad. Sci. USA 96:9112-9117 (1999). 3. Wolff, B., et al. "Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA." Chem Biol. 4:139-147 (1997). 4. Tunac, J.B., et al. "Novel antitumor antibiotics, CI-940 (PD 114,720) and PD 114,721. Taxonomy, fermentation and biological activity." J. Antibiot. 38:460-465 (1985). |
Get the Best Promotions
