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LGALS1, Recombinant, Mouse, aa1-135, His-Tag (AA410090, Gal-1, Galbp, Galectin-1, L-14.5, L14, Lect14)

Cat no: 138683

LGALS1, Recombinant, Mouse, aa1-135, His-Tag (AA410090, Gal-1, Galbp, Galectin-1, L-14.5, L14, Lect14)

LGALS1 is a member of the beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This protein is an autocrine negative growth factor that regulates cell proliferation. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes, thus LGALS1 has immunosuppressive and anti-inflammatory properties. LGALS1 also regulates tumor angiogenesis and is a target for angiostatic cancer therapy. \n\nSource:\nRecombinant protein corresponding to aa1-135 from mouse LGALS1 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~17kD (159aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSH GTWGTEHREP AFPFQPGSIT EVCITFDQAD LTIKLPDGHE FKFPNRLNME AINYMAADGD FKIKCVAFE MACGLV ASNLNLKPGE CLKVRGEVAS DAKSFVLNLG KDSNNLCLHF NPRFNAHGDA NTIVCNTKED\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138683

Size

100ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.15M sodium chloride, 10% glycerol.

Purity

~95% (SDS-PAGE)

References

1. Ilarregui JM., et al. (2009). Nat Immunol. 10(9):981-91. 2. Gauthier L., Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13014-9.

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