Home  >  Products  >  LGALS3BP, Recombinant, aa19-585, T7-Tag (M2BP, Galectin-3-binding Protein, Basement Membrane Autoantigen p105, Lectin Galactoside-binding Soluble 3-binding Protein, Mac-2-binding Protein, Tumor-associated Antigen 90K)

LGALS3BP, Recombinant, aa19-585, T7-Tag (M2BP, Galectin-3-binding Protein, Basement Membrane Autoantigen p105, Lectin Galactoside-binding Soluble 3-binding Protein, Mac-2-binding Protein, Tumor-associated Antigen 90K)

Cat no: 149824


Supplier: United States Biological
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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage- associated lectin known as Mac-2 and also binds galectin 1. Source: Recombinant protein corresponding to LGALS3BP, fused to T7 tag at N-terminal expressed in E.coli. Molecular Weight: ~65.2kD Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: 149824
Size: 50ug
Form: Supplied as a liquid in 10mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% sodium azide, 10mM DTT.
Purity: ~95%

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