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Lgals7, Recombinant, Mouse, aa1-136, His-Tag (Galectin-7, Pig1)

Cat no: 138684

Lgals7, Recombinant, Mouse, aa1-136, His-Tag (Galectin-7, Pig1)

Lglas7, also known as galectin7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium. Lgals7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. \n\nSource:\nRecombinant protein corresponding to aa1-136 from mouse Lgals7 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~17.6kD (159aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGS GKWGREERGT GIPFERGQPF EVLLIATEEG FKAVVGDDEY LHFHHRMPPA RVRLVEVGGD VQLHSVKIF MSATQHK TSLPQGVRVG TVMRIRGMVP DQAGRFHVNL LCGEEQGADA ALHFNPRLDT SEVVFNTKEQ\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138684

Size

100ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.1M sodium chloride, 2mM DTT, 20% glycerol.

Purity

~95% (SDS-PAGE)

References

1. Magnaldo T., et al. (1995) Dev Biol. 168(2):259-71. 2. Magnaldo T., et al. (1998) Differentiation. 63(3):159-68.

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