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LGALS8, Recombinant, Mouse, aa1-316, His-Tag (Lectin Galactose Binding Soluble 8, 1200015E08Rik, AI326142, D13Ertd524e, Lgals-8)

Cat no: 138685

LGALS8, Recombinant, Mouse, aa1-316, His-Tag (Lectin Galactose Binding Soluble 8, 1200015E08Rik, AI326142, D13Ertd524e, Lgals-8)

LGALS8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cell matrix interactions in a manner similar to the selectin subgroup of C-type lectins. \n\nSource:\nRecombinant protein corresponding to aa1-316 from mouse LGALS8 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~38KD (339aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGS RFKRSSCIVC NTLTQEKWGW EEITYDMPFR KEKSFEIVFM VLKNKFQVAV NGRHVLLYAH RISPEQIDTV GIYGKVNIHS IGFRFSSDLQ MLSLNNL QNIIYNPIIP YVGTITEQLK PGSLIVIRGH VPKDSERFQV DFQLGNSLKP RADVAFHFNP SMETSALGLT QINRENIQKP GKLQLSLPFE ARLNASMGPG RTVVIKGEVN TNARSFNVDL VAGKTRDIAL HLNPRLNVKA FVRNSFLQDA WGEEERNITC FPFSSGMYFE MIIYCDVREF KVAINGVHSL EYKHRFKDLS SIDTLSVDGD IRLLDVRSW\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138685

Size

50ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.15M sodium chloride, 1mM DTT, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Kobayashi T., et al. (2010) Leukemia. 24(4):843-50. 2. Streetly MJ., et al. (2010) Blood. 115(19):3939-48.

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