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LGALSL, Recombinant, Human, aa1-172, His-Tag (Galectin-related Protein, GRP, HSPC159)

Cat no: 137106

LGALSL, Recombinant, Human, aa1-172, His-Tag (Galectin-related Protein, GRP, HSPC159)

Galectin-related protein, also known as LGALSL, is a 172 amino acid protein that contains one galectin domain. Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and also play a role in tumor progression, pre-mRNA splicing and apoptosis. However, LGALSL does not appear to bind carbohydrates or lactose because the critical residues required for binding are not conserved. \n\nSource: \nRecombinant protein corresponding to human LGALSL, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~21.4kD (195aa) (MALDI-TOF)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMAGSVAD SDAVVKLDDG HLNNSLSSPV QADVYFPRLI VPFCGHIKGG MRPGKKVLVM GIVDLNPESF AISLTCGDSE DPPADVAIEL KAVFTDRQLL RNSCISGERG EEQSAIPYFP FIPDQPFRVE ILCEHPRFRV FVDGHQLFDF YHRIQTLSAI DTIKINGDLQ ITKLG\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137106

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.1M NaCl, 20% glycerol, 1mM DTT.

Purity

~90% (SDS-PAGE)

References

1. Zhou D., et al. (2008) Proteins. 71:1582-1588. 2. Walti M A., et al. (2008) Proteins. 72:804-808.

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