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Lipoprotein, Low Density, Oxidized, Human (LDL)

Cat no: L2601-10M

Lipoprotein, Low Density, Oxidized, Human (LDL)

Low density lipoprotein (LDL) oxidative modification is one of the major processes involved in atherosclerosis along with other degenerative disorders. Oxidised LDL is preferentially accumulated by macrophages which become so called "foam cells" within the atheromatous plaque and contributes to the accumulation of cholesterol, typical of atherosclerosis.\n\nApplications:\nSuitable for use in Functional Assays. Other applications not tested. \n\nRecommended Dilutions:\nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nMay be stored at 4 degrees C. Do not freeze. Aliquots are stable for 4 weeks. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

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SPECIFICATIONS

Catalog Number

L2601-10M

Size

2mg

Form

Supplied as a liquid in PBS, 0.3 mM EDTA

Purity

Purified to homogeneity by ultra-centrifugation. Oxidized using 20uM cupric sulphate in PBS at 37C for 24 hours. Oxidation is terminated with excess EDTA. The level of oxidation is measured using TBARS (Thiobarbituric acid reactive substances) determination using a Malondialdehyde (MDA) standard.

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