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Lomeguatrib

Cat no: 015667


Supplier: United States Biological
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Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts.
Catalogue number: 015667
Size: 25mg
Alternative names: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine; 6-[(4-Bromo-2-thienyl)methoxy] -1H-purin-2-amine; 2-Amino-6-(4-bromothiophen-2-ylmethoxy)-9H-purine; PaTrin 2;
References: Reinhard, et al.: J. Med. Chem., 44, 4050 (2001), Barvaux, et al.: Mol. Cancer Ther., 3, 1215 (2004), Clemons, et al., Br. J. Cancer, 93, 1152 (2005),

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