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Luzopeptin A (Antibiotic BBM-928A)

Cat no: L7520

Luzopeptin A (Antibiotic BBM-928A)

Luzopeptin is a member of the echinomycin (quinomycin A) class of antitumor and antibiotic agents that act by formation of a stable DNA complex by bis-intercalation. Luzopeptin A has also been shown to be a potent inhibitor of HIV-1 reverse transcriptase. \n\nDMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water

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SPECIFICATIONS

Catalog Number

L7520

Size

1mg

Form

Tan solid

Purity

>99%

References

1. BBM-928, a new antitumor antibiotic complex I. Production, isolation, characterization and antitumor activity. Ohkuma, H. et al., J. Antibiot. 1980, 33, 1087. 2. Screening for inhibitors of avian myeloblastosis virus reverse transcriptase and effect on the replication of AIDS virus. Inouye Y.J. Antibiot. 1987, 40, 100. 3. Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening. Leroy J.L. et al. Biochemistry. 1992, 31, 1407.

Alternative Names

Antibiotic BBM-928A

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