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Lymphotoxin beta Receptor, Murine/Human IgG1 Fc Fusion Protein (LTBR, LT-beta-R, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor Superfamily Member 3) (Preservative Free)

Cat no: L8015-04

Lymphotoxin beta Receptor, Murine/Human IgG1 Fc Fusion Protein (LTBR, LT-beta-R, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor Superfamily Member 3) (Preservative Free)

A soluble fusion protein consisting of 10 residual amino acids from murine CD8 alpha leader sequence (KPQAPELRGS), followed by the mature extracellular domain of murine LTbR (aa 28-221) fused to human IgG1 Fc. Molecular weight: 48.8kD. This protein runs at a higher apparent MW by SDS-PAGE due to glycosylation.\n\nAmino Acid Sequence:\nKPQAPELRGSSQPQLVPPYRIENQTCWDQDKEYYEPMHDVCCSRCPPGEFVFAVCSRSQDTVCKTCPHNSYNEHWNHLSTCQLCRPCDIVLGFEEVAPCTSDRKAECRCQPGMSCVYLDNECVHCEEERLVLCQPGTEAEVTDEIMDTDVNCVPCKPGHFQNTSSPRARCQPHTRCEIQGLVEAAPGTSYSDTICKNPPEPGAMPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK\n\nMouse CD8 signal peptide and linker: KPQAPELRGS\nMouse LTBR (a.a. 28-221): SQPQL......EPGAM\nFc of human IgG1, Accession #P01857 (a.a.100-330): PKSCD....LSPGK\n\nTransfectant Cell Line: HEK293\n\nApplications: \nSuitable for the use in the study of enzyme kinetics, screening inhibitors and selectively profiling. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nFor long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for 6 months.

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SPECIFICATIONS

Catalog Number

L8015-04

Size

100ug

Form

Supplied as a liquid in 10 mM phosphate, 138 mM sodium chloride and 2.7mM potassium chloride, pH 7.4. Endotoxin: ~0.001EU/ug.

Purity

(same/more than)90% by SDS-PAGE

References

1. Crowe, P.D., et al., Science. 1994. Apr 29;264(5159):707-10. 2. Wu, M.Y., et al., J Biol Chem. 1999. Apr 23;274(17):11868-73.

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