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LYN (2H8D) Antibody

LYN (2H8D) Antibody

Cat no: 252697

Supplier: ABBIOTEC
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Lyn (p53/56 Lyn) is a membrane-associated protein tyrosine kinase (PTK) mostly e, Xenopus/Amphibian,pressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B-cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues. Lyn can also be regulated by IL-2 and IL-3. Lyn is a member of the src family of non-receptor protein tyrosine kinases,Porcineredominantly e, Xenopus/Amphibian,pressed in haematopoietic tissues. Like all members of the src family, lyn is thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. It is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI).
Catalogue number: 252697
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: P07948
Antigen: Purified recombinant fragment of LYN e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG2b
Clonality: 2H8D7
Additional info: Lck/Yes-related novel protein tyrosine kinase; V-yes-1; Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn; JTK8; FLJ26625
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