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Lysosome-associated Membrane Protein-1 (LAMP1, LAMP-1, CD107a Antigen, LAMPA, LGP120, Lysosome-associated Membrane Glycoprotein 1 Precursor) (PE)

Cat no: L9190-10F

Lysosome-associated Membrane Protein-1 (LAMP1, LAMP-1, CD107a Antigen, LAMPA, LGP120, Lysosome-associated Membrane Glycoprotein 1 Precursor) (PE)

LAMP1 (Lysosome-associated membrane protein-1; also known as CD107a) is a 100-130kD member of the LAMP family of glycoproteins. It is expressed in lysosomal and plasma membranes of macrophages, NK and T cells, and is essential for the formation of phagolysosomes, along with LAMP2. On the cell surface, LAMP1 also presents carbohydrates to selectins. Mature human LAMP1 is a 389 aa type I transmembrane glycoprotein. It contains a 354aa luminal/extracellular domain (ECD) (aa28-381) and a 12aa cytoplasmic tail (aa405- 416). The ECD has two large looping regions (aa28-193 and 227-381) plus multiple N- and O-linked glycosylation sites. \n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMaybe stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

L9190-10F

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder in 25ug antibody, 1ml saline, 0.5% BSA, 0.1% sodium azide. Reconstitute with 40-50% glycerol, PBS.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2b

Additional Info

Recognizes human LAMP-1.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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