Magnetic beads are surface activated magnetic particles, intended for covalent immobilization of proteins (e.g. antibodies, enzymes), peptides, nucleic acids or other molecules of interest. Different surface modifications and bead sizes allow for choosing the optimal product for the right molecule to be coupled, and for the intended application.
After coupling the molecule of interest (ligand) is coupled to the magnetic particles, the resulting beads can be used in downstream applications such as:
? Isolating specific target proteins, antibodies, nucleic acids, cells, viruses, etc. (preparative applications)
? Detecting specific target proteins, nucleic acids, cells, viruses, etc. (diagnostic applications)
? Immobilizing enzymes, thereby enhancing stability and minimizing auto-catalysis. Magnetic collection of the particle/enzyme complex allows to remove the enzyme from the reaction, and to reuse it in a new reaction.
Applications:
Functionalization of the MagSi beads
Storage and Stability:
May be stored at 4 degrees C. For long-term storage, store at 4 degrees C. Do not freeze! Store beads in well closed vial and in upright position to prevent drying of the beads since this makes them more difficult to resuspend and may decrease their activity. Vortex bead suspension well before use. Beads are stable for at least 6 months.
Use of MagDetect(TM) Magnetic Separators:
Magnetic separators are required to work with magnetic beads. MagDetect(TM) Separators work with all MagDetect(TM) products as well as all competitive magnetic beads on the market.
M2106-80, Magnetic Bead Separator 12+12 for MagDetect(TM) beads in 12x1.5ml and 12x 2ml tubes.
M2106-81, Magnetic Bead Separator 96 well for MagDetect(TM) beads in
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