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MAGOHB, Recombinant, Human, aa1-148, His-Tag (Protein Mago Nashi Homolog 2, Mago-nashi Homolog B (Drosophila), Mago, Magoh, MGN2)

Cat no: 137111

MAGOHB, Recombinant, Human, aa1-148, His-Tag (Protein Mago Nashi Homolog 2, Mago-nashi Homolog B (Drosophila), Mago, Magoh, MGN2)

MAGOHB is involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway. Also, it is interacts with RBM8A and is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, UPF3B, UPF2 and ALYREF/THOC4. \n\nSource: \nRecombinant protein corresponding to human MAGOHB, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~19.7kD (171aa) (MALDI-TOF)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMAVASDF YLRYYVGHKG KFGHEFLEFE FRPDGKLRYA NNSNYKNDVM IRKEAYVHKS VMEELKRIID DSEITKEDDA LWPPPDRVGR QELEIVIGDE HISFTTSKIG SLIDVNQSKD PEGLRVFYYL VQDLKCLVFS LIGLHFKIKP I\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137111

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 30% glycerol, 0.15M NaCl.

Purity

~90% (SDS-PAGE)

References

1. Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J,., et al. 2006, 314(5797):268-74.

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