Home  >  Products  >  Malformin C (5-L-Leucine-Malformin A, BRN 4896114, (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-])
Malformin C (5-L-Leucine-Malformin A, BRN 4896114, (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-])

Malformin C (5-L-Leucine-Malformin A, BRN 4896114, (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-])

Cat no: 045030

Supplier: United States Biological
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Peptide antibiotic. Induces root curvature and malformation in plants. Antibacterial, antimalarial and antitrypanosomal. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 3 years after receipt when stored at -20 degrees C.
Catalogue number: 045030
Size: 250ug
Purity: >97% (HPLC)
Alternative names: 5-L-Leucine-Malformin A, BRN 4896114, (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-]
References: Product Reference: ?Malformin C, a new metabolite of Aspergillus niger: R.J. Anderegg, et al.; JACS 98, 3365 (1976) ?Production and antibacterial activity of malforming C, a toxic metabolite of Aspergillus niger: B. Kobbe, et al.; Appl. Environ. Microbiol. 33, 996 (1977) ?Fungal malformins inhibit bleomycin-induced G2 checkpoint in Jurkat cells: K. Hagimori, et al.; Biol. Pharm. Bull. 30, 1379 (2007) ?Solid-phase synthesis and biological activity of malformin C and its derivatives: Y. Kojima, et al.; J. Antibiot. (Tokyo) 62, 681 (2009) ?

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