Mannan-binding Lectin Horse (15C5) Antibody

Cat no: 250356

Supplier: ABBIOTEC

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Description
Additional Information

Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates,Mouse,BL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum. This antibody is specific for human MBL from plasma or serum, but cross-reacts strongly with MBL from horse and swine.

Catalogue number:	250356
Reactivities:	Human, Porcine
Size:	0.2 mg
Accession:	P11226
Antigen:	MBL purified from human donor plasma and adsorbed onto aluminum hydro, Xenopus/Amphibian,ide
Format:	Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1/k
Clonality:	15C5
Additional info:	Mannose-binding protein C; MBP-C; MBP1; Mannose-binding lectin; mannan-binding protein; MBL2; MBL