MAP2K4 (2D10) Antibody

Cat no: 252676

Supplier: ABBIOTEC

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Description
Additional Information

MAP2K4 (Mitogen-activated protein kinase kinase 4) is a 399-amino acid protein (~45 kDa), belongs to the family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. MEK-4 (also called MEK4/MKK4) activates both p38 and JNK MAP kinases MKK4 is a central mediator in the stress activated protein kinase signaling pathway that responds to a number of cellular and environmental stressors. By phosphorylating MAP kinases such as JNK,Mouse,KK4 can ultimately transmit stress signals to nuclear transcription factors that mediate various processes including proliferation, apoptosis, and differentiation. Its distinct biological functions have been identified for MKK4 including a role in development, hepatogenesis and metastasis suppression.

Catalogue number:	252676
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P45985
Antigen:	Purified recombinant fragment of MAP2K4 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse Ig M
Clonality:	2D10D8,4G11B2,2D10C4,2D10C3
Additional info:	Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKK; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; MAP2K4