MAP4K4 (3C7B) Antibody

Cat no: 252792

Supplier: ABBIOTEC

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Description
Additional Information

MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1,Mouse,AP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.

Catalogue number:	252792
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	O95819
Antigen:	Purified recombinant fragment of MAP4K4(aa400-500) e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3C7B5
Additional info:	Mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; Nck-interacting kinase HGK; KIAA0687; NIK MAP4K4