MAPK1 (activated) Antibody

Cat no: 251762

Supplier: ABBIOTEC

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Description
Additional Information

Mitogen-activated protein kinase 1 (MAP kinase 1) is involved in both the initiation and regulation of meiosis,Mouse,itosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. MAP kinase 1 acts as a transcriptional repressor. MAP kinase 1 binds to a [GC]AAA[GC] consensus sequence. MAP kinase 1 represses the e, Xenopus/Amphibian,pression of interferon gamma-induced genes. MAPK1 is activated by phosphorylation on Thr-185 and Tyr-187 in response to insulin and NGF. Both phosphorylations are required for activity. This antibody binds to the diphosphorylated form.

Catalogue number:	251762
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunocytochemistry, Immunohistochemistry
Size:	0.1 mg
Accession:	P28482
Antigen:	Recombinant diphosphorylated human MAPK1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by goat anti-mouse IgG affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	IL-13
Additional info:	Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; E, Xenopus/Amphibian,tracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; MAPK1; ERK2; PRKM1; PRKM2