PBLD, also known as MAWBP, is a phenazine biosynthesis-like protein (PhzF) family. Expressed in most tissues, PBLD is the only representative of the PhzF family in the human genome. It is participate in the MAPK signaling pathway. Involved in multiple basic cellular functions, expression of PBLD is elevated in several disease processes, including Insulin resistance, folate deficiency and hypotension.
Source:
Recombinant corresponding to aa1-288 of human PBLD protein, fused to His-tag at N-terminus, expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MKLPIFIADA FTARAFRGNP AAVCLLENEL DEDMHQKIAR EMNLSETAFI RKLHPTDNFA QSSCFGLRWF TPASEVPLCG HATLASAAVL FHKIKNMNST LTFVTLSGEL RARRAEDGIV LDLPLYPAHP QDFHEVEDLI KTAIGNTLVQ DICYSPDTQK LLVRLSDVYN RSFLENLKVN TENLLQVENT GKVKGLILTL KGEPGGQTQA FDFYSRYFAP WVGVAEDPVT GSAHAVLSSY WSQHLGKKEM HAFQCSHRGG ELGISLRPDG RVDIRGGAAV VLEGTLTA
Molecular Weight: 33.9kD (308aa) confirmed by MALDI-TOF
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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